Best Readings in Nanoscale Communication Networks

Recently, IEEE Communications Society has published The Best Readings in Nanoscale Communication Networks, which covers a wide range of hot topics, encouraging innovations in this technology by assisting academic and industrial researchers in devoting their effort to highly targeted resources organized by categories.



Introductory materials

MolCom books

A list of books and book chapters dealing with MolCom:

  • Molecular Communication, T. Nakano, A. W. Eckford, T. Haraguchi, Cambridge University Press, October 2013, ISBN: 9781107023086
  • Fundamentals of Diffusion-Based Molecular Communication in Nanonetworks, M. and I.F. Akyildiz, Foundations and Trends in Networking: Vol. 8: No. 1-2, pp 1-147, 2014,
  • Molecular Communications and Nanonetworks, B. Atakan, Springer-Verlag New York, 2014, ISBN: 978-1-4939-0739-7,
  • Nanoscale Communication Networks, S. F. Bush, Artech House, 2010, ISBN: 978-1-60807-003-9


MolCom surveys

Some interesting suvery papers on MolCom:

  1. I. F. Akyildiz et al., “Nanonetworks: A New Communication Paradigm”, Computer Networks, 2008,
  2. T. Nakano et al., “Molecular communication and networking: Opportunities and challenges”, IEEE Trans. on NanoBioscience, 2012,
  3. T. Nakano et al., “ Molecular Communication Among Biological Nanomachines: A Layered Architecture and Research Issues”, IEEE Trans. on NanoBioscience, 2014,
  4. L. Felicetti et al. “Applications of molecular communications to medicine: A survey”, Nano Communication Networks, 2016,
  5. N. Farsad et al. “A Comprehensive Survey of Recent Advancements in Molecular Communication”, IEEE Comm. Surveys & Tutorials, in press,


MolCom standard

IEEE P1906.1 is an IEEE standards working group sponsored by the IEEE Communications Society Standards Development Board whose goal is to develop a definition and common framework for nanoscale and molecular communication. Since this is an emerging technology, the standard is meant to elicit innovation by determining a common definition, terminology, framework, goals, metrics, and use-cases designed to encourage greater innovation and enable the technology to advance at a faster rate. The standard defines the fundamental definition and building blocks of nanoscale communications.


Advanced readings

We have identified a set of specific papers in molecular communications, able to provide a more focused contribution on specific aspects of molecular communications. Up to now, we have identified the following topics

  • Specificity:
  • Perturbation
  • Field
  • Motion
  • Message Carrier
  • Medium
  • Molecular absorptions
  • Molecular flow and feedbacks

Contributions focused upon the service of enabling a nanoscale Message Carrier to convey its information to a desired receiver or class of receivers while avoiding loss of message carriers along the way from reception by other receivers or classes of receivers.

  • T.A. Sanders, E. Llagostera, and M. Barna, “Specialized Filopodia Direct Long-range Transport of SHH During Vertebrate Tissue Patterning,” Nature, vol. 497, no. 7451, pp. 628–632, 30 May 2013.
  • S. Roy, H. Huang, S. Liu, and T.B. Kornberg, “Cytoneme-Mediated Contact-Dependent Transport of the Drosophila Decapentaplegic Signaling Protein,” Science, vol. 343, no. 6173, 21 February 2014.
  • L. Bardwell, X. Zou, Q. Nie, and N. L. Komarova, “Mathematical Models of Specificity in Cell Signaling,” Biophysical Journal, vol. 92, no. 10, pp. 3425-3441, 15 May 2007.

Contributions focused upon novel ideas involving nanoscale encoding, signaling, and modulation.

  • M.J. Moore, T. Suda, and K. Oiwa, “Molecular Communication: Modeling Noise Effects on Information Rate,” IEEE Transactions on NanoBioscience, vol. 8, no. 2, pp. 169-180, June 2009.

Contributions emphasizing directionality and coordinated control of Message Carriers at the nanoscale.

  • I.V. Dokukina, M.E. Gracheva, E.A. Grachev, and J.D. Gunton, “Role of Network Connectivity in Intercellular Calcium Signaling,” Physica D: Nonlinear Phenomena, vol. 237, no. 6, pp. 745-754, 15 May 2008.
  • S. Schuster, M. Marhl, and T. Hofer, “Modelling of Simple and Complex Calcium Oscillations,” European Journal of Biochemistry, vol. 269, no. 5, pp. 1333-1355, March 2002.
  • Y. Tang and H.G. Othmer, “Frequency Encoding in Excitable Systems with Applications to Calcium Oscillations,” Proceedings of the National Academy of Sciences, vol. 29, no. 17, pp. 7869-7873, 15 August 1995.

Contributions related to understanding and engineering basic Message Carrier movement at the nanoscale.

  • W.H. Bossert, and E.O. Wilson, “The Analysis of Olfactory Communication Among Animals,” Journal of Theoretical Biology, vol. 5, no. 3, pp. 443–469, November 1963.
  • I. Llatser, A. Cabellos-Aparicio, and E. Alarcon, “Networking Challenges and Principles in Diffusion-Based Molecular Communication,” IEEE Wireless Communications, vol. 19, no. 5, pp. 36-41, October 2012.
  • S. Kadloor, R.S. Adve, and A.W. Eckford, “Molecular Communication Using Brownian Motion with Drift,” IEEE Transactions on NanoBioscience, vol. 11, no. 2, pp. 89-99, June 2012.
  • K. Francis and B.O. Palsson, “Effective Intercellular Communication Distances are Determined by the Relative Time Constants for Cyto/Chemokine Secretion and Diffusion,” Proceedings of the National Academy of Sciences, vol. 94, no. 23, pp. 12258-12262, 11 November 1997.
  • S. Klumpp, T.M. Nieuwenhuizen, and R. Lipowsky, “Self-Organized Density Patterns of Molecular Motors in Arrays of Cytoskeletal Filaments,” Biophysical Journal, vol. 88, no. 5, pp. 3118-32, May 2005.
  • N. Farsad, A.W. Eckford, and S. Hiyama, “A Markov Chain Channel Model for Active Transport Molecular Communication,” IEEE Transactions on Signal Processing, vol. 62, no. 9, pp. 2424-2436, May 2014.
  • S. Balasubramaniam and P. Lio, “Multi-Hop Conjugation Based Bacteria Nanonetworks,” IEEE Transactions on NanoBioscience, vol. 12, no. 1, pp. 47-59, March 2013.

Message Carrier
Contributions regarding the design and construction of Message Carriers at the nanoscale.

  • S. Hiyama, T. Inoue, T. Shima, Y. Moritani, T. Suda, and K. Sutoh, “Autonomous Loading, Transport, and Unloading of Specified Cargoes by Using DNA Hybridization and Biological Motor-Based Motility,” Small, vol. 4, no. 4, pp. 410-415, April 2008.
  • Frank Walsh, Sasitharan Balasubramaniam, “Reliability and Delay Analysis of Multi-hop Virus-based Nanonetworks,” IEEE Transactions on Nanotechnology, 12: 5. pp. 674-684, September 2013.

Contributions emphasizing novel media in which nanoscale Message Carriers reside.

  • Y. Chahibi, M. Pierobon, S.O. Song, and I.F. Akyildiz, “A Molecular Communication System Model for Particulate Drug Delivery Systems,” IEEE Transactions on Biomedical Engineering, vol. 60, no. 12, pp. 3468-3483, December 2013.
  • N. Farsad, A.W. Eckford, S. Hiyama, and Y. Moritani, “On-Chip Molecular Communication: Analysis and Design,” IEEE Transactions on NanoBioscience, vol. 11, no. 3, pp. 304-314, September 2012.

Molecular absorptions
Contributions regarding mechanisms and models about absorption of Message Carriers and their temporal statistics.

  • H. Yilmaz, A. Heren, T. Tugcu, and C.-B. Chae. Three-dimensional channel characteristics for molecular communications with an absorbing receiver. IEEE Communications Letters, 18(6):929–932, June 2014.
  • A. Akkaya, H. Yilmaz, C. Chae, and T. Tugcu. Effect of receptor density and size on signal reception in molecular communication via diffusion with an absorbing receiver. IEEE Communications Letters, 19(2):155–158, Feb 2015.
  • L. Felicetti, M. Femminella, G. Reali, J. Daigle, M. Malvestiti, and P. Gresele. Modeling CD40-based molecular communications in blood vessels. IEEE Transactions on NanoBioscience, 13(3):230–243, 2014.

Molecular flows and feedbacks
Contributions regarding mechanisms for regulating continuous molecular flow, with special focus on drug delivery applications.

  • T. Nakano, Y. Okaie, and A. V. Vasilakos. Transmission rate control for molecular communication among biological nanomachines. IEEE Journal on Selected Areas in Communications, 31(12, supplement):835-846, 2013.
  • L. Felicetti, M. Femminella, G. Reali, T. Nakano, and A. V. Vasilakos. TCP-like molecular communications. IEEE Journal on Selected Areas in Communications, 32(12):2354-2367, 2014.